5-Amino-1MQ

5-Amino-1MQ selectively blocks the enzyme nicotinamide N-methyltransferase (NNMT). NNMT normally converts nicotinamide into N1-methylnicotinamide, but by inhibiting this process, 5-Amino-1MQ helps preserve nicotinamide levels and increases the availability of NAD+, an important coenzyme for cellular energy and metabolism.

This molecule increases the availability of nicotinamide, a precursor required for NAD+ synthesis. Higher intracellular NAD+ levels may stimulate Sirtuin 1, a regulatory protein associated with DNA repair, inflammation control, and metabolic function.

5-Amino-1MQ has shown several possible therapeutic effects in early research, including:

• Lowering cholesterol levels
• Supporting blood glucose regulation
• Promoting muscle regeneration
• Reducing inflammation

5-Amino-1MQ has generated interest as a potential strategy for addressing obesity, metabolic syndrome, and certain age-related disorders.