CJC-1295 No DAC

CJC-1295 No DAC is a synthetic analogue of Human Growth Hormone-Releasing Hormone designed with targeted amino acid substitutions to improve stability and enhance its usefulness in research settings. Its structure includes several key modifications:

• D-alanine at position 2 to increase resistance to enzymatic breakdown
• Glutamine at position 8 to minimize asparagine rearrangement and amide hydrolysis
• Alanine at position 15 to improve bioactivity
• Leucine at position 27 to reduce methionine oxidation.

These changes collectively contribute to improved molecular stability and functional consistency in laboratory applications. Frequently used in research examining muscle development, recovery processes, and metabolic function. Its capacity to elevate endogenous growth hormone levels makes it of interest in investigations related to athletic performance, body composition changes, and physiological function. It is also being explored in the context of age-related muscle decline and metabolic imbalance, where it may help inform longevity and health-related research.